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Some companies where you can upload LOs will show you a preview of what will print and what will be cropped. With the company I work for, I know that they will crop 1/8 inch on 3 sides and 1/4 inch for the binding, so when I start a LO, I set guides for those dimensions and stay within them. Then, if I want something to the edge of the page, I just put it to the guide and I know it won't be cut off!
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